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History

Researchers experimented with organ transplantation on animals and humans in the 18th century. There were many failures over the years, but by the mid-20th century, scientists were performing successful organ transplants. Transplants of kidneys, livers, hearts, pancreata, intestine, lungs, and heart-lungs are now considered routine medical treatment.

Important medical breakthroughs such as tissue typing and immunosuppressant drugs allow for more organ transplants and a longer survival rate for recipients. The most notable development in this area was Jean Borel's discovery of an immunosuppressant drug in the mid-1970s. Cyclosporine was approved for commercial use in November 1983.

Unfortunately, the need for organ transplants continues to exceed the supply of organs. But as medical technology improves and more donors become available, the number of people who live longer and healthier lives continues to increase each year.

1954: 1st successful kidney transplant

1st successful kidney transplant*

1954
1966: 1st successful kidney-pancreas transplant

First successful pancreas/kidney transplant

1966
1967: 1st successful liver transplant

First successful liver transplant*

1967
1968: 1st isolated pancreas transplant

First isolated pancreas transplant

1968
1968: 1st successful heart transplant

First successful heart transplant

1968
1981: 1st successful heart-lung transplant

First successful heart-lung transplant

1981
1983: 1st successful single lung transplant

First successful single lung transplant*

1983
1986: 1st successful double lung transplant

First successful double lung transplant*

1986
1989: 1st successful living-related liver transplant

First successful living-related liver transplant

1989
1990: 1st successful living-related lung transplant

First successful living-related lung transplant

1990

* Transplant was the first of its kind in the world.

 

Organ Procurement & Transplantation Network

This is an official U.S. Government Web site managed by the Health Resources and Services Administration, U.S. Department of Health & Human Services.